Modern physics has experienced major advancements at the beginning of the twentieth century. However, these developments gave rise to new questions and a new perception of the universe from the perspective of both physics and philosophy. As a result, the questions which we had been asking in order to understand the universe acquired a different character. Physicists were the first to seek answers to these questions. Subsequently, a physicist-philosopher type emerged, pioneered by founders of modern physics such as Planck, Einstein, Heisenberg. This article analyses the various arguments made by the mentioned physicist-philosophers in an attempt to answer the current problems in physics, philosophy and science. Lastly, this article explains the relationship between philosophy and science and in conclusion, illustrates the existing conflicts and causal relation between them.